Dear Daisy Dog
Molly, our 3-year-old spayed Labrador, has taken phenylpropanolamine (PPA) for urinary leakage for six months. Because PPA controls the problem well, Molly is supposed to continue taking it for the remainder of her life.
I haven’t been able to find any long-term studies that prove the drug is safe to give for many years. Do you feel the benefits of PPA outweigh the risks of giving it nearly her entire lifetime?
My golden retriever sister leaked urine and benefitted from PPA. She took it for many years without difficulty.
Most veterinarians make the same observation, that side effects to PPA are rare in dogs, even when it’s given for many years. Unfortunately, formal research studies on the drug’s long-term safety and effectiveness have not been done.
Therefore, most veterinarians recommend that dogs take the lowest effective dose to minimize potential side effects.
Because PPA can affect the cardiovascular system, some vets suggest that a dog taking PPA have blood pressure and EKG checked yearly. Most advise annual blood work for any dog taking a long-term medication.
If your veterinarian thinks PPA is right for Molly, you can feel comfortable knowing that most other veterinarians would agree.